| Publications: |
| Kristin M. Huntoon, Yanping Wang, Cheryl A. Eppolito, Karen
W. Barbour, Franklin G. Berger, Protul A. Shrikant, and Heinz
Baumann. The acute
phase protein haptoglobin regulates host
immunity. J
Leukoc Biol. 2008 Apr 24. [Epub ahead of print] Barbour KW and Berger FG. Cell Death in response to antimetabolites directed at thymidylate synthase. Cancer Chemotherapy and Pharmacolgy. 2008. Feb;61(2):189-201. Epub 2007 Mar 30. Tucker JM, Murphy JT, Kisiel N, Diegelman P, Barbour KW, Davis C, Medda M, Alhonen L, Janne J, Kramer DL, Porter CW, Berger FG. Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase.. Cancer Res. 2005 Jun 15;65(12):5390-8. Barbour
KW,
Goodwin RL, Guillonneau F, Wang Y, Baumann H, Berger FG. Functional
diversification during evolution of the murine alpha(1)-proteinase
inhibitor
family: role of the hypervariable reactive center Barbour KW, Wei F, Brannan C, Flotte TR, Baumann H, Berger FG. The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure. Genomics. 2002 Nov;80(5):515-22. Barbour
KW, Davis T, White A, Baumann H, Berger FG. Haptoglobin,
inflammation,
and tumorigenesis in the MIN mouse. Redox Rep. 2001;6(6):366-8. Mol Biochem Parasitol. 2001 Oct;117(2):129-36. Kitchens
ME, Forsthoefel AM, Barbour KW, Spencer HT, Berger FG. Mechanisms
of
acquired resistance to thymidylate synthase inhibitors: the role of
enzyme
stability. Mol Pharmacol. 1999 Nov;56(5):1063-70. Mol Biol Evol. 1998 Mar;15(3):312-25. Goodwin RL, Barbour KW, Berger FG. Expression of the alpha 1-proteinase inhibitor gene family during evolution of the genus Mus. Mol Biol Evol. 1997 Apr;14(4):420-7. Reilly RT, Barbour KW, Dunlap RB, Berger FG. Biphasic binding of 5-fluoro-2'-deoxyuridylate to human thymidylate synthase. Mol Pharmacol. 1995 Jul;48(1):72-9. Hughey CT, Barbour KW, Berger FG, Berger SH. Functional effects of a naturally occurring amino acid substitution in human thymidylate synthase. Mol Pharmacol. 1993 Aug;44(2):316-23. Hughey CT, Barbour KW, Berger FG, Berger SH. Genetic variation in thymidylate synthase confers resistance to 5-fluorodeoxyuridine. Adv Exp Med Biol. 1993;339:67-76. Barbour KW, Hoganson DK, Berger SH, Berger FG. A naturally occurring tyrosine to histidine replacement at residue 33 of human thymidylate synthase confers resistance to 5-fluoro-2'-deoxyuridine in mammalian and bacterial cells. Mol Pharmacol. 1992 Aug;42(2):242-8. Chaudhuri A, Barbour KW, Berger FG. Evolution of messenger RNA structure and regulation in the genus Mus: the androgen-inducible RP2 mRNAs. Mol Biol Evol. 1991 Sep;8(5):641-53. Barbour KW, Berger SH, Berger FG. Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase. Mol Pharmacol. 1990 Apr;37(4):515-8. Rheaume C, Barbour KW, Tseng-Crank J, Berger FG. Molecular genetics of androgen-inducible RP2 gene transcription in the mouse kidney. Mol Cell Biol. 1989 Feb;9(2):477-83. Lin T, Blaisdell J, Barbour KW, Thompson EA. Transient activation of c-myc protooncogene expression in Leydig cells by human chorionic gonadotropin. Biochem Biophys Res Commun. 1988 Nov 30;157(1):121-6. Berger SH, Barbour KW, Berger FG. A naturally occurring variation in thymidylate synthase structure is associated with a reduced response to 5-fluoro-2'-deoxyuridine in a human colon tumor cell line. Mol Pharmacol. 1988 Oct;34(4):480-4. Lucas KL, Barbour KW, Housley PR, Thompson EA Jr. A Biochemical and molecular characterization of the glucocorticoid receptor of lymphosarcoma P1798 variants. Mol Endocrinol. 1988 Mar;2(3):291-9. Barbour KW, Berger SH, Berger FG, Thompson EA Jr. Glucocorticoid regulation of the genes encoding thymidine kinase, thymidylate synthase, and ornithine decarboxylase in P1798 cells. Mol Endocrinol. 1988 Jan;2(1):78-84. Berger SH, Davis ST, Barbour KW, Berger FG. The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations. Adv Exp Med Biol. 1988;244:59-69. |