mouse

Recent Publications:

Cooperation between an intrinsically disordered region and a helical segment is required for ubiquitin-independent degradation by the proteasome.

Melo SP, Barbour KW, Berger FG.

J Biol Chem. 2011 Oct 21;286(42):36559-67. 

Functional dissection of the N-terminal degron of human thymidylate synthase.

Melo SP, Yoshida A, Berger FG.

Biochem J. 2010 Oct 25;432(1):217-26.


Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway.

Zhang X, Wan G, Mlotshwa S, Vance V, Berger FG, Chen H, Lu X.

Cancer Res. 2010 Sep 15;70(18):7176-86. Epub 2010 Jul 28.


Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice.

Baltgalvis KA, Berger FG, Pena MM, Mark Davis J, White JP, Carson JA.

J Appl Physiol. 2010 Oct;109(4):1155-61. Epub 2010 Jul 22.



Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .

Huang X, Gibson LM, Bell BJ, Lovelace LL, Pena MM, Berger FG, Berger SH, Lebioda L.

Biochemistry. 2010 Mar 23;49(11):2475-82.


The intrinsically disordered N-terminal domain of thymidylate synthase targets the enzyme to the ubiquitin-independent proteasomal degradation pathway.

Pena MM, Melo SP, Xing YY, White K, Barbour KW, Berger FG.

J Biol Chem. 2009 Nov 13;284(46):31597-607. Epub 2009 Sep 21.



The interaction of a high-fat diet and regular moderate intensity exercise on intestinal polyp development in Apc Min/+ mice.

Baltgalvis KA, Berger FG, Pena MM, Davis JM, Carson JA.

Cancer Prev Res (Phila). 2009 Jul;2(7):641-9. Epub 2009 Jun 23.

 

Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein.

Watanabe J, Grijalva V, Hama S, Barbour K, Berger FG, Navab M, Fogelman AM, Reddy ST.

J Biol Chem. 2009 Jul 3;284(27):18292-301. Epub 2009 May 11.


Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.

Yang X, Wood PA, Ansell CM, Ohmori M, Oh EY, Xiong Y, Berger FG, Pena MM, Hrushesky WJ.

J Biochem. 2009 Mar;145(3):289-97. Epub 2008 Dec 23.


Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc ( Min/+ ) mouse.

Baltgalvis KA, Berger FG, Pena MM, Davis JM, White JP, Carson JA.

Pflugers Arch. 2009 Mar;457(5):989-1001. Epub 2008 Aug 19.


Period 2 mutation accelerates ApcMin/+ tumorigenesis.

Wood PA, Yang X, Taber A, Oh EY, Ansell C, Ayers SE, Al-Assaad Z, Carnevale K, Berger FG, Pena MM, Hrushesky WJ.

Mol Cancer Res. 2008 Nov;6(11):1786-93.


Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer.

Thangaraju M, Cresci G, Itagaki S, Mellinger J, Browning DD, Berger FG, Prasad PD, Ganapathy V.

J Gastrointest Surg. 2008 Oct;12(10):1773-81; discussion 1781-2. Epub 2008 Jul 26.


The acute phase protein haptoglobin regulates host immunity.

Huntoon KM, Wang Y, Eppolito CA, Barbour KW, Berger FG, Shrikant PA, Baumann H.

J Leukoc Biol. 2008 Jul;84(1):170-81. Epub 2008 Apr 24.


Interleukin-6 and cachexia in ApcMin/+ mice.

Baltgalvis KA, Berger FG, Pena MM, Davis JM, Muga SJ, Carson JA.

Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R393-401. Epub 2007 Dec 5.

Cell death in response to antimetabolites directed at thymidylate synthase.

Barbour KW, Berger FG.

Cancer Chemother Pharmacol. 2008 Feb;61(2):189-201. Epub 2007 Mar 30.



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